The stress connection
نویسندگان
چکیده
منابع مشابه
The Angiotensin II–Mechanical Stress Connection
A series of studies conducted 20 years ago, documenting the cardiac hypertrophy phenotype and its underlying signaling mechanism induced by angiotensin II (Ang II) and mechanical stress, showed a remarkable similarity between the effect of the Gαq agonist and that of mechanical forces on cardiac hypertrophy. Subsequent studies confirmed the involvement of autocrine/paracrine mechanisms, includi...
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itations encountered in gene therapy, such as low gene expression, difficulties in producing adequate vector amounts, immune responses caused by non-specific transduction, and non-specific gene integration could be overcome by improving vector targeting. The bulk of the book (Parts 1 and 2) is dedicated to articles about transductional targeting strategies, meaning ways to design or manipulate ...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2010
ISSN: 1740-1526,1740-1534
DOI: 10.1038/nrmicro2375